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Human molecular genetics / Tom Strachan and Andrew P. Read.

By: Contributor(s): Language: English Publisher: Boca Raton, Florida : CRC Press, 2019Copyright date: ©2019Edition: Fifth editionDescription: xiii, 770 sidor illustrationer 28 cmContent type:
  • text
  • still image
Media type:
  • unmediated
Carrier type:
  • volume
ISBN:
  • 0815345895
  • 9780815345893
  • 0367002507
  • 9780367002503
Subject(s): DDC classification:
  • 611.01816 23/swe
LOC classification:
  • QH431
Other classification:
  • Vbba
Contents:
PART 1: Basics of DNA, Chromosomes, Cells, Development, and Inheritance -- 1. Basic Principles of Nucleic Acid Structure and Gene Expression -- 2. Fundamentals of Cells and Chromosomes -- 3. Fundamentals of Cell-Cell Interactions and Immune System Biology -- 4. Aspects of Early Mammalian Development, Cell Differentiation, and Stem Cells -- 5. Patterns of Inheritance -- PART 2: Understanding Genomes -- 6. Core DNA Technologies: Amplifying DNA, Nucleic Acid Hybirdization, and DNA Sequencing -- 7. Analyzing the Structure and Expression of Genes and Genomes -- 8. Principles of Genetic Manipulation of Mammalian Cells -- 9. Uncovering the Architecture and Workings of the Human Genome -- 10. Gene Regulation and the Epigenome -- PART 3: Genetic Variation Between Individuals and Species -- 11. An Overview of Human Genetic Variation -- 12. Human Population Genetics -- 13. Comparative Genomics and Genome Evolution -- 14. Human Evolution -- PART 4. Human Genetic Disease -- 15. Chromosomal Abnormalities and Structural Variants -- 16. Molecular Pathology: Connecting Phenotypes to Genotypes -- 17. Mapping and Identifying Genes for Monogenic Disorders -- 18. Complex Disease: Identifying Susceptibility Factors and Understanding Pathogenesis -- 19. Cancer Genetics and Genomics -- PART 5. Applied Human Molecular Genetics -- 20. Genetic Testing in Healthcare and The Law -- 21. Modeling Organisms and Modeling Disease -- 22. Genetic Approaches to Treating Disease
Summary: Human Molecular Genetics has been carefully crafted over successive editions to provide an authoritative introduction to the molecular aspects of human genetics, genomics and cell biology. Maintaining the features that have made previous editions so popular, this fifth edition has been completely updated in line with the latest developments in the field. Older technologies such as cloning and hybridization have been merged and summarized, coverage of newer DNA sequencing technologies has been expanded, and powerful new gene editing and single-cell genomics technologies have been added. The coverage of GWAS, functional genomics, stem cells, and disease modeling has been expanded. Greater focus is given to inheritance and variation in the context of populations and on the role of epigenetics in gene regulation.
Holdings
Item type Current library Shelving location Call number Status Date due Barcode Item holds
Course literature Biblioteket HKR Biblioteket 611 Strachan Available 11156000190174
Course literature Biblioteket HKR Biblioteket 611 Strachan Available 11156000190176
Course literature Biblioteket HKR Biblioteket 611 Strachan Available 11156000190178
Course literature Biblioteket HKR Biblioteket 611 Strachan Available 11156000190179
Dayloan Biblioteket HKR Biblioteket 611 Strachan Available 11156000190177
Total holds: 0

Enhanced descriptions from Syndetics:

Human Molecular Genetics has been carefully crafted over successive editions to provide an authoritative introduction to the molecular aspects of human genetics, genomics and cell biology.

Maintaining the features that have made previous editions so popular, this fifth edition has been completely updated in line with the latest developments in the field. Older technologies such as cloning and hybridization have been merged and summarized, coverage of newer DNA sequencing technologies has been expanded, and powerful new gene editing and single-cell genomics technologies have been added. The coverage of GWAS, functional genomics, stem cells, and disease modeling has been expanded. Greater focus is given to inheritance and variation in the context of populations and on the role of epigenetics in gene regulation.

Key features:

Fully integrated approach to the molecular aspects of human genetics, genomics, and cell biology Accessible text is supported and enhanced throughout by superb artwork illustrating the key concepts and mechanisms Summary boxes at the end of each chapter provide clear learning points Annotated further reading helps readers navigate the wealth of additional information in this complex subject and provides direction for further study Reorganized into five sections for improved access to related topics Also new to this edition - brand new chapter on evolution and anthropology from the authors of the highly acclaimed Human Evolutionary Genetics

A proven and popular textbook for upper-level undergraduates and graduate students, the new edition of Human Molecular Genetics remains the 'go-to' book for those studying human molecular genetics or genomics courses around the world.

Includes bibliographical references and index.

PART 1: Basics of DNA, Chromosomes, Cells, Development, and Inheritance -- 1. Basic Principles of Nucleic Acid Structure and Gene Expression -- 2. Fundamentals of Cells and Chromosomes -- 3. Fundamentals of Cell-Cell Interactions and Immune System Biology -- 4. Aspects of Early Mammalian Development, Cell Differentiation, and Stem Cells -- 5. Patterns of Inheritance -- PART 2: Understanding Genomes -- 6. Core DNA Technologies: Amplifying DNA, Nucleic Acid Hybirdization, and DNA Sequencing -- 7. Analyzing the Structure and Expression of Genes and Genomes -- 8. Principles of Genetic Manipulation of Mammalian Cells -- 9. Uncovering the Architecture and Workings of the Human Genome -- 10. Gene Regulation and the Epigenome -- PART 3: Genetic Variation Between Individuals and Species -- 11. An Overview of Human Genetic Variation -- 12. Human Population Genetics -- 13. Comparative Genomics and Genome Evolution -- 14. Human Evolution -- PART 4. Human Genetic Disease -- 15. Chromosomal Abnormalities and Structural Variants -- 16. Molecular Pathology: Connecting Phenotypes to Genotypes -- 17. Mapping and Identifying Genes for Monogenic Disorders -- 18. Complex Disease: Identifying Susceptibility Factors and Understanding Pathogenesis -- 19. Cancer Genetics and Genomics -- PART 5. Applied Human Molecular Genetics -- 20. Genetic Testing in Healthcare and The Law -- 21. Modeling Organisms and Modeling Disease -- 22. Genetic Approaches to Treating Disease

Human Molecular Genetics has been carefully crafted over successive editions to provide an authoritative introduction to the molecular aspects of human genetics, genomics and cell biology. Maintaining the features that have made previous editions so popular, this fifth edition has been completely updated in line with the latest developments in the field. Older technologies such as cloning and hybridization have been merged and summarized, coverage of newer DNA sequencing technologies has been expanded, and powerful new gene editing and single-cell genomics technologies have been added. The coverage of GWAS, functional genomics, stem cells, and disease modeling has been expanded. Greater focus is given to inheritance and variation in the context of populations and on the role of epigenetics in gene regulation.

Imported from: zcat.oclc.org:210/OLUCWorldCat (Do not remove)